p53 Status in Stromal Fibroblasts Modulates Tumor Growth in an SDF1-Dependent Manner
نویسندگان
چکیده
منابع مشابه
p53 status in stromal fibroblasts modulates tumor growth in an SDF1-dependent manner.
The p53 tumor suppressor exerts a variety of cell-autonomous effects that are aimed to thwart tumor development. In addition, however, there is growing evidence for cell nonautonomous tumor suppressor effects of p53. In the present study, we investigated the impact of stromal p53 on tumor growth. Specifically, we found that ablation of p53 in fibroblasts enabled them to promote more efficiently...
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ژورنال
عنوان ژورنال: Cancer Research
سال: 2010
ISSN: 0008-5472,1538-7445
DOI: 10.1158/0008-5472.can-10-1146